Within the University of Lisbon School of Medicine
- Member of the Directive Committee (1993-1995)
- Member of the Curriculum Committee (1995-2000)
- Member of the National Examination Board for Foreign Doctors (1996-2000)
- Member of the Pre-Registration Year Committee (1997-2003)
- Member of the Department of Medical Education (1996-2000)
- Director, Center for Evidence Based Medicine (2000- )
- Member of the Distance Learning Committee (2003- )
- Member of the Medical Informatics Committee (2005- )
- Chief Executive, Institute for Higher Education, University of Lisbon School of Medicine (2009- )
- Member, Cabinet of Innovation and Entrepreneurship (2017- )
- Director, Department of Medical Education (2015- )
- Head, Institute of Environmental Health (2017- )
- Head, Institute of Preventive Medicine and Public Health (2017- )
- President of the Scientific Council of the Institute for Evidence Based Health (2019- )
Within the Ministry of Health
- Member of the Pharmacy and Therapeutics Committee of the Regional Health Authority, Lisbon (1997- 2001)
- President, National Committee for Drug Advertising, the Portuguese Institute of Pharmacy and Drugs (the Portuguese FDA) (2000-2004)
- Member, Drug Reimbursement Committee, at the Portuguese Institute of Pharmacy and Drugs (the Portuguese FDA) (1997-2004)
- Sub-Director for Clinical Research and Guidelines Implementation, the National Institute for Quality in Healthcare (1999-2005)
- Member, The National Committee for Research Priorities (2002-2005)
- Member, National Quality Assurance Committee (2010)
- Coordinator, Forum for Orphan Drugs. National System of Health Technology Assessment in Portugal (SiNATS) INFARMED (2015-16)
- Coordinator, Medical Decision Support Systems, Portuguese Medical Association and Ministry of Health (2018)
Other
- President, Scholarship Association of the Luso-American Foundation, Lisboa (1997- 2002)
- Member, Grant/Scholarship Evaluating Committee, Luso-American Foundation, Lisboa (1999- )
- Member, Steering Committee, Best Evidence Medical Education of the Association for Medical Education in Europe (2000-present)
- Member, Steering Committee, Ibero-GPC (RedGuias) (2002-present)
- Member, Board of Trustees, Guideline International Network (GIN) (2006-present)
- Fellow, American College of Physicians (2008)
- Director, Harvard Medical School Portugal Program (2009- 2011)
- Scientific consultant, Health Consumer Powerhouse (2011-2012)
- President, World Scientific Committee Univadis (2012- )
- Partner, International Consortium on Health Outcomes Measurements (2012- )
- Director, Portuguese Collaborating Center of the Iberoamerican Cochrane Network and Cochrane Portugal (2011- )
- Partner, International Consortium on Health Outcomes Measurements, 2012
- Chair, Scientific Board of Univadis, MSD (2012- )
- Chair, Best Evidence Medical Education Review Editorial Board, Association for Medical Education in Europe (2013- )
- Member, Clinical Practice Guideline Committee – European Society of Cardiology (2014-16)
- Director, Cochrane Portugal (2015- )
- Fellow, European Society of Cardiology. Elected 2015
- President, National Commission for Continuous Professional Development, Portuguese Medical Association (2017-20)